Cardiovascular Genetics and Genomics

This comprehensive and concise presentation of genetic factors in cardiovascular disease and their response to therapy consolidates knowledge of this high-interest and emerging topic. Covering broad areas of contemporary genomic medicine and specific cardiovascular diseases, this book is a must for anyone seeking to better understand this rapidly developing field. Provisional list of contents.

Section A: Principles.

1 Principles of genetics and genomics.

2 Candidate gene and genome-wide association approaches.

3 A primer in statistical methods in genetics.

4 Ethical, legal, and social issues.

5 The role of ethnicity in managing cardiovascular patients.

6 Moving to the bedside: When? How?.

Section B: Specific cardiovascular disease.

7 Genomics and Atrial Arrhythmias.

8 Ventricular arrhythmias and sudden death.

9 Hypertrophic Cardiomyopathy and Other Forms of Hypertrophy.

10 Genetics and genomics of dilated cardiomyopathy.

11 Arrhythmogenic Right Ventricular Cardiomyopathy.

12 Genetics of atherosclerosis.

13 Hypertension.

14 Stroke Genomics.

15 Thrombosis.

16 Case study: warfarin pharmacogenetics from single to multiple genes.

17 Pharmacogenetics and Pharmacogenomics.

?This excellent book highlights the many advances in this field, and educates cardiovascular practitioners about what aspects of cardiology are likely to lend themselves to pharmacogenetics and tailored therapy.? (Doody?s, 2009) Dan M. Roden, M.D., Professor of Medicine and Pharmacology, Director, Oates Institute for Experimental Therapeutics, Assistant Vice-Chancellor for Personalized Medicine, Vanderbilt University School of Medicine.